Hyperthermia and immunomodulation

Toraya-Brown S., Fiering S. Local tumour hyperthermia as immunotherapy for metastatic cancer. International Journal of Hyperthermia, 30:8, 531-539. DOI: 10.3109/02656736.2014.968640. Link to article: http://dx.doi.org/10.3109/02656736.2014.968640

Hurwitz M., Stauffer PR. Hyperthermia, radiation and chemotherapy: the role of heat in multidisciplinary cancer care. Department of Radiation Oncology Faculty Papers (2014). Paper 69. http://jdc.jefferson.edu/radoncfp/69

Repasky EA., Evans SS., Dewhirst MW. Temperature Matters! And Why It Should Matter to Tumor Immunologists. Cancer Immunology Research (2013) 1(4); 210–6. DOI: 10.1158/2326-6066.CIR-13-0118

Rubner Y., Wunderlich R., Rühle P-F., Kulzer L., Werthmöller N., Frey B., Weiss E-M., Keilholz L., Fietkau R., Gaipl US. How does ionizing irradiation contribute to the induction of anti-tumor immunity? Frontiers in Oncology (2012) 2: 75. DOI: 10.3389/fonc.2012.00075

Mace TA., Zhong L., Kokolus KM., Repasky EA. Effector CD8+ T cell IFN-γ production and cytotoxicity are enhanced by mild hyperthermia. International Journal of Hyperthermia (2012) 28(1): 9–18. DOI:10.3109/02656736.2011.616182

Skitzki JJ., Repasky EA., Evans SS. Hyperthermia as an immunotherapy strategy for cancer. Current Opinion in Investigational Drugs (2009) 10(6): 550-558

Peer AJ., Grimm MJ., Zynda ER., Repasky EA. Diverse immune mechanisms may contribute to the survival benefit seen in cancer patients receiving hyperthermia. Immunologic Research (2010) Mar; 46(1-3): 137-54. DOI: 10.1007/s12026-009-8115-8.

Multhoff G. Hyperthermia classic commentary: Activation of natural killer (NK) cells by heat schock protein 70. International Journal of Hyperthermia (2009) 25(3): 176-179. DOI: 10.1080/02656730902835672

Baronzio G., Gramaglia A., Fiorentini G. Hyperthermia and Immunity. A Brief Overview. In vivo (2006) 20: 689-696.

Multhoff G., Mizzen L., Winchester CC., Milner CM., Wenk S., Eissner G., et al. Heat shock protein 70 (Hsp70) stimulates proliferation and cytolytic activity of natural killer cells. Experimental Hematology (1999) 27(11):1627–1636. DOI:10.1016/S0301-472X(99)00104-6