Hyperthermia in medicine

The development of hyperthermia in modern medicine, initiated more than a century ago by Dr. William Coley, gained momentum in the mid-70s of the twentieth century, along with the first clinical trials implemented in the US and in Europe.In the first place, hyperthermia, as an exogenous raising of body temperature, became interested in radiotherapists, quickly […]

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Taxonomy of hyperthermia

In order to arrange the terminology of particular types and ranges of hyperthermia, the following taxonomic criteria were adopted: ⦁ Classification in relation to the temperature range ⦁ Classification relative to the body heating area ⦁ Classification for the heating factor ⦁ Classification according to the invasiveness criterion

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Biology of hyperthermia

Biological effects of hyperthermia are widely discussed in research and demonstration articles (see the section „Bibliography„).The synthesis of this knowledge is as follows: A – Expression of ligand and other molecules on the surface of tumor cellsincrease in the presence of MHCI major histocompatibility complex, NKG2D and NKG2DL receptors and MICA receptor ligands B – […]

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Hyperthermia in oncology

Hyperthermia + Radiotherapy Hyperthermia + Chemotherapy Hyperthermia + Immunotherapy Hyperthermia in palliative care

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Hyperthermia non-oncological

In non-oncological indications almost exclusively systemic hyperthermia is used.

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Clinical trials

Although, in contrast to the pharmaceutical industry, the medical hyperthermia sector currently has much smaller funds for financing clinical trials, their number is growing dynamically in recent years. Of all the above-mentioned clinical trials, only five were entirely financed by the equipment manufacturers, and all other by research centers. The niche character of the hyperthermia […]

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Bibliography

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Hyperthermia Societies

PTHO – Polish Society for Hyperthermic Oncology (PL) ESHO – European Society for Hyperthermic Oncology (EU) DGHT – German Hyperthermia Society (DE) STM – Society for Thermal Medicine (USA)

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